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1 article(s) from Devi, Nisha

Morita–Baylis–Hillman reaction of 3-formyl-9H-pyrido[3,4-b]indoles and fluorescence studies of the products

Nisha Devi and
Virender Singh

Beilstein J. Org. Chem. 2022, 18, 926–934, doi:10.3762/bjoc.18.92

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Figure 1: Few examples of β-carboline-based drugs and bioactive natural products.

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Figure 2: 1/3-Formyl-9H-β-carboline: new synthons for the synthesis of β-carboline-fused and substituted fram...

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Figure 3: A summary of previous reports toward exploration of 3-formyl-9H-β-carbolines.

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Scheme 1: Synthesis of 3-formyl-9H-pyrido[3,4-b]indole derivatives.

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Scheme 2: Synthesis of C-3 substituted pyrido[3,4-b]indole MBH derivatives (7 and 8).

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Scheme 3: Synthesis of C-3 substituted pyrido[3,4-b]indole MBH derivatives 10.

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Figure 4: Library of C-3-substituted pyrido[3,4-b]indole MBH derivatives 7, 8 and 10.

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Figure 5: Results of optimization for fluorescence studies: a) contact time; b) concentration; c) solvent.

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Figure 6: Pictorial representation of structure–fluorescence activity relationship of C-3 substituted pyrido[...

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Published 26 Jul 2022

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